Certainty of genuine treatment increases drug responses among intellectually disabled patients

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Certainty of genuine treatment increases drug responses among intellectually disabled patients

OBJECTIVE To determine the placebo component of treatment responses in patients with intellectual disability (ID). METHODS A statistical meta-analysis comparing bias-corrected effect sizes (Hedges g) of drug responses in open-label vs placebo-controlled clinical trials was performed, as these trial types represent different certainty of receiving genuine treatment (100% vs 50%). Studies in fr...

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Children with an intellectual disability often demonstrate lack of cooperation during dental treatment and require behavioral management. A child with mild intellectual disability can be managed adequately using restraints and medication. However, in cases of profound intellectual disability, dental treatment under general anesthesia is usually required. In cases where the patient is an intelle...

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Over the past thirty years, Problem Solving Therapy (PST) has been shown to be an effective treatment for many different problems and patient populations (Nezu, 2004). Among its many clinical applications, PST interventions were developed for persons with intellectually disabilities (ID), where improving problem-solving skills led to adaptive behavioral improvements (Nezu, Nezu, & Arean 1991). ...

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Effect Site Concentrations of Propofol for Dental Treatment under Deep Sedation in Intellectually Disabled Patients

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ژورنال

عنوان ژورنال: Neurology

سال: 2017

ISSN: 0028-3878,1526-632X

DOI: 10.1212/wnl.0000000000003934